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14.4 Vaccination

First line drugs Second line drugs Specialist drugs Secondary care drugs

 

 

Useful sources of information

 

1. Click the following link for The routine immunisation schedule (from Autumn 2018)

 

2. Department of Health. The Green Book

  • The Green Book has the latest information on vaccines and vaccination procedures for all the vaccine preventable infectious diseases that may occur in the UK.

 

3. Public Health England  (Tel: 020 8200 4400)

 

4. MHRA: Live attenuated vaccines: avoid use in those who are clinically immunosuppressed

 

Travel

 

Vaccines

Vaccine Fees and Charges

 

BCG (bacillus calmette-guérin) vaccine

(BCG Vaccine SSI®)  (Amber 1)

Notes:

  • Injection (powder for suspension), freeze-dried preparation of live bacteria of a strain derived from the bacillus of Calmette and Guérin.
  • This is an intradermal vaccine.
  • This SSI vaccine must be suspended with 1ml of the Diluted Sauton SSI solvent only.

 

 

Diagnostic agents 

Tuberculin PPD (Mantoux) U  (Amber 1)

  • Injection, 20 units/ml (2 units/0.1ml dose) (for routine use), 1.5ml vial; 100 units/ml (10 units/0.1ml dose), 1.5ml vial

 

 

Cholera

Cholera vaccine

  • oral suspension

 

 

Diphtheria containing vaccines       

 

  • Injection (Infanrix®-IPV+Hib, Pediacel®, Boostrix-IPV®, Infanrix IPV®, Repevax®, Revaxis®) 

 

 

Haemophilus influenzae type B vaccine    

Menitorix®

  • Inj conjugate vaccine containing: Haemophilus influenzae type B vaccine, meningococcal group C (Hib/MenC)

     

 

 

Hepatitis A vaccine       

Hepatitis A vaccine

  • Injection (Avaxim®, Havrix® monodose, Epaxal®, Vaqta®, Havrix® Junior Monodose)      
        

 

 

Hepatitis A with Hepatitis B Vaccine

  • Inj (Ambirix®, Twinrix® Adult, Twinrix® Paed)

 

 

Hepatitis A vaccine with typhoid vaccine

  • Inj (Hepatyrix®, ViATIM®) Amber 1

 

Notes:

  • Hepatitis A and typhoid vaccine has been included for instances where both vaccines are required and it is not practical to administer both vaccines separately.
  • Licensed for use as a booster even though hepatitis A and typhoid vaccines have different booster requirements

 

 

Hepatitis B vaccine       

Hepatitis B vaccine

  • Engerix B® 20 micrograms per ml
  • HBvaxPRO® 10 micrograms per ml
  • HBvaxPRO® 40 micrograms per ml
  • Fendrix® 40 micrograms per ml       

Notes:

  • Fendrix® is for active immunisation against hepatitis B virus infection for patients (15 years of age and older) with renal insufficiency (including pre-haemodialysis and haemodialysis patients).

 

 

 

Human papilloma virus (HPV) vaccine

Human papilloma virus vaccine

  • Cervarix® 0.5ml prefilled syringe
  • Gardasil® 0.5ml prefilled syringe

 

 

Influenza vaccine       

Seasonal Influenza vaccine

  • 0.5ml pre-filled syringe       

Notes: 

 

 

Measles, Mumps and Rubella (MMR) vaccine live

Measles / mumps / rubella (MMR)

  • Injection (M-M-RvaxPro®, Priorix®)    

 

 

Meningococcal vaccines       

Meningococcal Group C conjugate vaccine

  • Inj (NeisVac-C®)   

Notes:

  • To be given as part of immunising individuals with asplenia, see current Green Book chapter 7

 

Meningococcal groups A, C, W135, and Y conjugate vaccine

  • Inj (Nimenrix®, Menveo®)

 

Meningococcal Group B vaccine

  • Inj (Bexsero®) 

 

 

 

Pneumococcal vaccines       

Pneumovax® II

  • 23-valent unconjugated pneumococal polysaccharide vaccine (PPV)       

Prevenar 13®

  • 13-valent pneumococcal polysaccharide conjugated vaccine (PCV)

 

 

Rabies vaccine       

Rabies vaccine  (Amber 1)

  • 1mL   

Notes:

 

Rotavirus vaccine

Rotavirus

  • Oral suspension, live attenuated rotavirus 1.5ml prefilled oral syringe

 

 

 

Typhoid vaccines       

Typhoid vaccine

  • Injection (Typhim Vi®)

 

 

Varicella-zoster vaccine       

Varicella-zoster vaccine  (Amber 1)

  • Injection

Notes:

  • Prevention of varicella infection (chickenpox) - (Varilrix®, Varivax®)

 

  • Prevention of herpes zoster (shingles) - (Zostavax®)       

 

  • The Department of Health recommends varicella-zoster vaccine for seronegative healthcare workers who come into direct contact with patients. Those with a history of chickenpox or shingles can be considered immune, but healthcare workers with a negative or uncertain history should be tested.

 

  • After vaccination, contact with the following should be avoided if a vaccine-related cutaneous rash develops within 4-6 weeks of the first or second dose:
  1. varicella-susceptible pregnant women
  2. individuals at high risk of severe varicella, including those with immunodeficiency or those receiving immunosuppressive therapy

 

  • Healthcare workers who develop a generalised papular or vesicular rash on vaccination should avoid contact with patients until the lesions have crusted.

 

Yellow fever vaccine

Yellow fever vaccines can only be given by designated Yellow Fever Vaccination Centres, details of which can be found on the NaTHNac website: www.nathnac.org.

Not available on NHS prescription

 

 

 

 

 

 

 

 

 

 

Traffic light status explained:

  • Green: Routine prescribing within licensed indication
  • Amber 1: specialist recommendation followed by GP initiation and continuation
  • Amber 2: specialist or GP initiation in line with local guideline after 1st line failure followed by GP continuation
  • Amber 3: specialist initiation and stabilisation followed by GP continuation
  • Amber SCG: specialist initiation and stabilisation followed by GP continuation in line with an agreed shared care guideline
  • Red: Hospital or specialist prescribing only

 

Return to Chapter: 14. Immunological Products and Vaccines

Last updated by: Dupe Fagbenro on 27-03-2019 17:02