11.6 Retinal Disorders
First line drugs | Second line drugs | Specialist drugs | Secondary care drugs |
Traffic light status (TLS) explained:
- Green: Routine prescribing within licensed indication
- Amber 1: specialist recommendation followed by GP initiation and continuation
- Amber 2: specialist or GP initiation in line with local guideline after 1st line failure followed by GP continuation
- Amber 3: specialist initiation and stabilisation followed by GP continuation
- Amber SCG: specialist initiation and stabilisation followed by GP continuation in line with an agreed shared care guideline
- Red: Hospital or specialist prescribing only
- Double Red: These medicines have been evaluated and rejected by MKPAG and are NOT approved for use within MK. They are not recommended for use because of lack of clinical effectiveness, cost effectiveness or safety.
11.6.1 Macular Degeneration
Aflibercept
- Eylea® Solution for intravitreal injection, 40mg per 1mL vials
Notes:
- Use as per NICE TA486: Aflibercept for treating choroidal neovascularisation (November 2017)
- Use as per NICE TA409: Aflibercept for treating visual impairment caused by macular oedema after branch retinal vein occlusion (September 2016)
- Use as per NICE TA346: Aflibercept for treating diabetic macular oedema (July 2015)
- Use as per NICE TA305: Aflibercept for treating visual impairment caused by macular oedema secondary to central retinal vein occlusion(February 2014)
- Use as per NICE TA294: Aflibercept solution for injection for treating wet age‑related macular degeneration (July 2013)
Ranibizumab
- Lucentis® 10mg/mL solution for injection in pre-filled syringe
Notes:
- Use as per NICE TA155: Ranibizumab and pegaptanib for the treatment of age-related macular degeneration (May 2012)
- Use as per NICE TA274:Ranibizumab for treating diabetic macular oedema(February 2013)
- Use as per NICE TA283: Macular oedema (retinal vein occlusion) - ranibizumab (May 2013)
- Use as per NICE TA298: Choroidal neovascularisation (pathological myopia) - ranibizumab (November 2013)
Verteporfin
- Injection powder for reconstitution 15mg vial
Notes:
- Use as per NICE TA68: Photodynamic therapy for wet age-related macular degeneration (Sept 2003)
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11.6.2 Macular oedema
Fluocinolone acetonide
- Iluvien® Intravitreal implant containing fluocinolone acetonide 190 micrograms in a disposable applicator
Notes:
- Use as per NICE TA301: Diabetic macular oedema - fluocinolone acetonide intravitreal implant (rapid review of TA271) (November 2013)
11.6.4 Vitreomacular traction
Ocriplasmin (Amber 2)
- Injection 125mcg
Notes:
- Use as per NICE TA297: Ocriplasmin for treating vitreomacular traction (Oct 2013)
Traffic light status (TLS) explained:
- Green: Routine prescribing within licensed indication
- Amber 1: specialist recommendation followed by GP initiation and continuation
- Amber 2: specialist or GP initiation in line with local guideline after 1st line failure followed by GP continuation
- Amber 3: specialist initiation and stabilisation followed by GP continuation
- Amber SCG: specialist initiation and stabilisation followed by GP continuation in line with an agreed shared care guideline
- Red: Hospital or specialist prescribing only
- Double Red: These medicines have been evaluated and rejected by MKPAG and are NOT approved for use within MK. They are not recommended for use because of lack of clinical effectiveness, cost effectiveness or safety.
Last updated by: Sheila Wood on 13-02-2019 13:57