1.6 Gastro-intestinal smooth muscle spasm
| First line drugs | Second line drugs | Specialist drugs | Secondary care drugs |
Traffic light status (TLS) explained:
- Green: Routine prescribing within licensed indication
- Amber 1: specialist recommendation followed by GP initiation and continuation
- Amber 2: specialist or GP initiation in line with local guideline after 1st line failure followed by GP continuation
- Amber 3: specialist initiation and stabilisation followed by GP continuation
- Amber SCG: specialist initiation and stabilisation followed by GP continuation in line with an agreed shared care guideline
- Red: Hospital or specialist prescribing only
Useful resources
National Guideline:
Antimuscarinics
Dicycloverine Hydrochloride
- Oral Solution 10mg/5mL
Hyoscine butylbromide
- Tablets 10mg
- Injection 20mg in 1mL (Hospital or Palliative Care Specialist Use Only)
Notes:
- Hyoscine butylbromide may be useful in gastro-intestinal disorders characterised by smooth muscle spasm and in terminal care, but its anticholinergic side effects limit its use.
- Drug Safety Update - Hyoscine butylbromide (Buscopan) injection: risk of serious adverse effects in patients with underlying cardiac disease (February 2017)
Antispasmodics
Mebeverine hydrochloride
- Tablets 135mg
Traffic light status (TLS) explained:
- Green: Routine prescribing within licensed indication
- Amber 1: specialist recommendation followed by GP initiation and continuation
- Amber 2: specialist or GP initiation in line with local guideline after 1st line failure followed by GP continuation
- Amber 3: specialist initiation and stabilisation followed by GP continuation
- Amber SCG: specialist initiation and stabilisation followed by GP continuation in line with an agreed shared care guideline
- Red: Hospital or specialist prescribing only
Return to Chapter: 1. Gastro-Intestinal System
Last updated by: Dupe Fagbenro on 06-02-2019 12:57
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BNF
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NICE
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Summary of product characteristics
